Methylation is an incredibly complex biochemical process that plays a ubiquitous role in the body’s maintenance. In very layman terms, it turns nutrients from the food that you eat into a type of fuel that your body uses to catalyse enzymes, which are involved in everything from mood regulation, fertility, detoxification of toxins and hormones, energy production, and vascular health.

In particular, having a dysregulated CAR - meaning it is either too high or too low - can lead to symptoms of depression, anxiety, affective disorders, chronic fatigue and increase risk of autoimmunity. This is because CAR has a unique ability to regular inflammation, blood sugar, as well as memory and recall due to the fact that the hippocampus is so tied in with CAR. It also plays a role in infection regulation and so can have far-reaching effects on the body’s resilience to viruses and bacteria.

Glutathione has been labelled as the mother of all antioxidants and the ultimate free radical quencher and detoxifier. We produce this molecule endogenously, primarily in the liver, using the precursor amino acids cysteine, glutamine and glycine, which come from the food that we eat. Research shows that as we increase in age our levels of glutathione gradually go down and deficiency of this antioxidant has been associated with Alzheimer’s and depression, as well as other chronic illnesses such as cancer.

Whilst increasing vegetables and fruit intake is crucial for improving health due to their richness in micronutrients, fibre and antioxidants, when it comes to brain health there are some key nutrients that cannot be found easily in a vegan diet that must be taken into consideration, if we want to keep the brain healthy on a long term basis.